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Focus Vitamins

Focus Select® Zinc Free AREDS2-Based Formula

Focus Select® Zinc Free AREDS2-Based Formula

Regular price $45.99
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  • Supports Macular Health
  • Does Not Contain Zinc
  • Safer For More Patients

Focus Select® Zinc Free is for patients whose physicians recommend a zinc-free AREDS2-based formula.

Focus Select® Zinc Free utilizes the latest improvements discovered in AREDS2®, replacing beta-carotene with lutein and zeaxanthin and eliminating zinc to offer a formulation that is safe for patients wishing to avoid zinc in their supplements. Our unique formulation not only provides powerful levels of the nutrients proven to be beneficial in the study, but it is safer for smokers and reduces the risk of side effects associated with zinc.

Focus Select® Zinc Free is produced in an NSF certified and FDA audited facility. As an extra measure, we conduct and approve a third-party certification of analysis for every active ingredient, on every lot, every time.

Ask your eye doctor if Focus Select® Zinc Free is the best choice for you.

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Customer Reviews

Based on 7 reviews
John Cook
Good, but...

I will continue to take these supplements on the advice of my doctor. At each visit, I show no signs of macular degenerative progress, but I have no way to know if this would be the case with or without the supplements.

Donna H.
Zinc free formula

Focus Zinc free Areds formula is essential for my AMD dry intermediate condition. I am grateful for the availability from Focus.


Been taking these for years.

Sarah Dorris

I’ll know if they are helping in Ayg

Robbin Sentell
Great Product well priced

The product works as expected. Focus ordering and delivery process makes it easy for me to use the product.


How was the Focus Select® formulation developed?

Focus Select is based on peer-reviewed findings and analysis of the Age-Related Eye Disease Studies (AREDS) conducted by the National Eye Institute (NEI), a division of the National Institute of Health.


In 1992, the National Eye Institute launched the large-scale AREDS study to investigate the impact of supplementation on patients with AMD. The 2001 findings demonstrated that high doses of antioxidant vitamins and minerals slowed the progression of AMD in people with intermediate AMD and those with Advanced AMD in one eye by an average of 25% over a five-year period.

Original AREDS formulation:

  • 500 mg of vitamin C
  • 400 international units of vitamin E
  • 15 mg beta-carotene
  • 80 mg zinc oxide
  • 2 mg copper as cupric oxide


AREDS2 was a follow-up study conducted to in effort to improve upon the original formula. The original AREDS contained beta-carotene, an antioxidant found to be associated with an increased risk of lung cancer in smokers in two large trials funded by the National Cancer Institute. The original formula also contained 80 mg of zinc, a level considered too high by some nutritionists and which is associated with side effects in some patients.

Modifications tested in AREDS2:

  • 10 mg of lutein and 2 mg zeaxanthin
  • 1000 mg omega-3 fatty acids
  • Removing beta-carotene
  • Reducing zinc levels to 25 mg

AREDS2 findings impacting supplementation:

  • Replacing the antioxidant beta-carotene with lutein and zeaxanthin in the AREDS2 trial resulted in a slight reduction in risk of advanced AMD compared to the original AREDS with beta-carotene
  • Adding Omega-3 fatty acids did not improve the risk of advanced AMD overall

Who should take Focus Select®?

Focus Select should only be considered by those at risk for developing advanced AMD. Prior to taking the levels of vitamins and minerals found in our formula, patients should speak with their doctor about the risk of developing advanced AMD and whether taking Focus Select is right for them.

Will taking Focus Select® cure AMD?

No. There are currently no treatments for dry AMD. While the AREDs formulations may slow the progression of dry AMD in people with moderate levels of disease by 25%, no supplement has demonstrated the ability to improve or restore vision.

Can patients take a daily multivitamin if they are taking Focus Select®?

Yes. Most people in the AREDS studies also took multivitamins. However, you should first consult with your primary care doctor and receive their approval to take a multivitamin in conjunction with Focus Select.

Can patients take a daily multivitamin instead of Focus Select®?

No. While a multivitamin has a broad spectrum of vitamins and minerals, it does not contain the high levels of specific antioxidants proven to be effective in the AREDS2 study.

Should patients consider changing to Focus Select® if they are on an original AREDS formula?

Yes. Replacing beta-carotene with lutein/zeaxanthin is safer for smokers and showed a lower risk of progression (18%) of AMD in AREDS subjects compared with those in the AREDS2 trial. Additionally, the 25 mg dose of zinc in lieu of 80 mg may prevent side common side effects associated with zinc.